Bioactive malt substances
Bioactive malt substances for Cosmetic Applications
In the cosmetics sector and the pharmaceuticals industry there is an increasing demand for innovative natural ingredients with a skin lightening function. The project aims to exploit the potential of malt and by-products of malt processing as well as beer production for the cosmetics industry. The intention is not to discard malt flours and so far unused residues from the processing of malted cereals as low-value residues or to feed them to cattle and pigs, but to redefine and evaluate them in order to develop new powerful active ingredients for the cosmetics industry.The primary goal is to identify and extract bioactive substances from malt and by-products and to test whether these compounds can be used to efficiently inhibit melanin synthesis in the skin. Based on this, innovative malt-based extracts and complexes of active agents with novel functionalities, such as tyrosinase inhibiting, melanin reducing and antioxidative properties, are developed.In the first and second year of the project, the focus was on the procurement of raw materials, the correct sample preparation and sample preparation as well as the optimization of the extraction process with subsequent extract characterization. A strong correlation between the polyphenol content and the antioxidative capacity of the extracts could be observed. In in vitro experiments, this effect leads to a proven inhibition of tyrosinase, which was also confirmed by cell culture analyses on melanocytes carried out by the service provider of VivaCell Biotechnology GmbH, Denzlingen. Further properties that have been demonstrated by tests on cell cultures are melanogenesis-inhibiting and partially anti-inflammatory effects
2017 - 2019
Bundesministerium für Wirtschaft und Energie, INNO-KOM Modul „Marktorientierte Forschung"
M. Sc. Martin Almendinger